GlossaryAcute Pancreatitis

Acute Pancreatitis

Updated June 18, 2026

Acute Pancreatitis is defined as the sudden onset of inflammation within the pancreas, an organ responsible for producing digestive enzymes and insulin. The condition occurs when these digestive enzymes, which are normally inactive until they reach the small intestine, become prematurely activated while still inside the organ. This process results in autodigestion, effectively causing the pancreas to digest itself and damaging surrounding tissues. In the CKD patient, this presents a significant diagnostic challenge. Unlike dogs, who often show obvious vomiting and abdominal pain, cats frequently exhibit vague symptoms such as profound lethargy and anorexia (refusal to eat). Diagnosis is typically confirmed through the feline Pancreatic Lipase Immunoreactivity (fPLI) test, a specific blood test that detects leakage of enzymes from inflamed pancreatic cells. There is no specific cure for the condition. Instead, management is supportive and focuses on maintaining hydration, controlling nausea with antiemetics, and providing aggressive pain relief (analgesia) to allow the organ time to heal.

Disclaimer: This content is for educational purposes only and does not constitute veterinary medical advice. Always consult with your primary care veterinarian or a veterinary internal medicine specialist regarding your cat’s specific condition.