Chronic Pancreatitis is defined as a persistent, low-grade inflammation of the pancreas that leads to permanent structural damage. Unlike the acute form which is a sudden crisis, the chronic form is a slow, progressive disease where healthy glandular tissue is gradually replaced by non-functional scar tissue (fibrosis) and atrophy. In the feline patient, this condition is notoriously difficult to detect because the clinical signs—such as intermittent vomiting, weight loss, and a waxing and waning appetite—are subtle and easily mimic Chronic Kidney Disease (CKD). It is frequently a component of Feline Triaditis, occurring alongside Inflammatory Bowel Disease (IBD) and liver inflammation. Over time, the destruction of pancreatic tissue can lead to Exocrine Pancreatic Insufficiency (EPI), where the cat can no longer digest food properly, or Diabetes Mellitus if the insulin-producing cells are destroyed. Diagnosis relies on a combination of history, the feline Pancreatic Lipase Immunoreactivity (fPLI) blood test, and ultrasound imaging which may show a shrunken or irregular pancreas. Management is lifelong and supportive, focusing on pain management, nausea control, and often dietary modification.
Disclaimer: This content is for educational purposes only and does not constitute veterinary medical advice. Always consult with your primary care veterinarian or a veterinary internal medicine specialist regarding your cat’s specific condition.